About the book: year / In the 4th edition (1st published in 1984, 2nd in 1993, 3rd in 1998) presents new data on acute and chronic viral hepatitis, methods of specific prevention and antiviral therapy recommended in world practice, treatment of hepatic encephalopathy, portal hypertension, ascites, and liver transplantation. All diseases are presented in accordance with the new classification of liver diseases. The section of clinical syndromes, laboratory and instrumental research methods has been expanded. The issues of etiology, pathogenesis, clinical picture, diagnosis, treatment of all the most important focal and diffuse liver diseases are covered. In accordance with modern advances in medicine, the chapters on viral hepatitis, autoimmune liver diseases, alcoholic disease, porphyrias, liver amyloidosis and pregnancy, liver vascular diseases have been significantly revised, and the chapter “Non-alcoholic steatohepatitis” has been introduced. Liver damage due to chronic infections, diseases of the hematopoietic organs, blood circulation, metabolic disorders, and under the influence of drugs and toxins are also considered; liver diseases in newborns and children. Much attention is paid to modern diagnostics and individualization of therapy. For therapists, gastroenterologists, surgeons, infectious disease specialists, pediatricians, scientists.